https://www.ferreiralab.com/research daily 0.75 2025-02-05 https://www.ferreiralab.com/home daily 1.0 2026-06-16 https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1632014089638-V92KTKH2JCYAOFXT1YSM/Ferreira%2CLeonardo-Microbiology.JPG Home - Leonardo Ferreira, PhD (Principal Investigator) Leonardo M. R. Ferreira, Ph.D. is an Assistant Professor of Pharmacology and Immunology and, by courtesy, of Regenerative Medicine and Cell Biology at the Medical University of South Carolina and the Hollings Cancer Center. He holds a B.Sc. in biochemistry from University of Coimbra, Portugal, a Ph.D. in biochemistry from Harvard University, and completed a postdoctoral fellowship at the University of California, San Francisco. Fascinated by the phenomenon of immune tolerance, his long term goal is to control how the immune system defines self and non-self. Such knowledge will allow the design and development of powerful new engineered immune cell therapies to fight autoimmune disease, cancer, and aging. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/6b19034d-78c7-4b8f-bdad-d916ab77e88d/AndrewBrim.jpg Home - Andrew Brim (PhD Student) Andrew Brim is a PhD student in the Biomedical Sciences Program. He graduated from the University of Florida with his B.S. in Biochemistry. While at UF, he also worked under Dr. Steven Bruner to elucidate the structure of clinically relevant SRP54 mutant proteins by x-ray crystallography. After graduating, he joined Dr. Hong Qin’s lab at Mayo Clinic Florida, where he helped develop novel CAR-T cell therapies by performing lentivirus plasmid cloning and in vivo animal studies. He joined the Ferreira Lab in 2026 and is interested in tailoring genetic modifications to improve CAR-based cellular therapies for the solid tumor microenvironment, infectious diseases, and autoimmune diseases. Andrew enjoys reading, baking, surfing, comedy podcasts and hanging out with his beagle. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/072e589b-87b0-4eb5-b097-afed55335008/MJValencia.jpg Home - MJ Valencia (PhD Student) MJ Valencia is a PhD student in the Biomedical Sciences Program. She earned her bachelor’s degree in Microbiology and Immunology from The University of Texas at San Antonio. MJ is passionate about understanding the mechanisms that drive inflammation and autoimmune disease, with the goal of contributing to the development of innovative immunotherapies and targeted treatments. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/25c9a8d1-6e7a-4c6b-ac5c-7e0f9b7c2f75/AvikChattopadhyay.jpg Home - Avik Chattopadhyay, PhD (Postdoctoral Scholar) Avik Chattopadhyay, Ph.D. is a postdoctoral scholar in the lab from India. Avik completed his B.Sc. at the University of Calcutta and M.Sc. at the Banaras Hindu University in Zoology. He earned his Ph.D. in Immunology from the Indian Institute of Science, Bangalore, under the supervision of Prof. Dipankar Nandi (who graduated with a PhD from the lab of Nobel laureate J. P. Allison). Avik’s doctoral research focused on the metabolic responses of tumor cells to interferon-gamma, a critical determinant in immunotherapy outcomes. Furthermore, his investigations led to the discovery of novel anti-inflammatory compounds identified through high-throughput screening against interferon-gamma-induced nitric oxide production. Avik has been recognized with numerous accolades, including the Sun Pharma Science Foundation Science Scholar Award 2023 in Pharmaceutical Sciences. Currently, his research as a postdoctoral scholar is dedicated to advancing precise and effective immunotherapy strategies targeting challenging cancers and inflammatory diseases. Avik aspires to establish himself as an independent researcher, fostering interdisciplinary collaborations to innovate solutions in disease biology. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/e0e1fec5-8c69-479b-8cb6-b946013e66f5/ErinOConnor.jpg Home - Erin O’Connor (Research Scientist) Erin O'Connor is a recent graduate of the College of Charleston, where she obtained a B.S. in Biology with a minor in Chemistry. As a research scientist, she hopes to contribute to a greater understanding of the role of genetic engineering in treating physical and mental illnesses. In the future, she plans to pursue a Ph.D. in Genetics. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/e2ad083b-52f0-41bc-adf4-39435c6b72ce/IosifGershteyn.jpg Home - Iosif Gershteyn (Visiting Scholar) Iosif M. Gershteyn is a systems immunologist focusing on harnessing computation in application to autoimmune disorders and aging. He is the Chairman of Ajax Biomedical Foundation, which supports several projects in partnership with the Ferreira lab, including the interrogation of interactions between diet and autoimmune disease and developing immunomodulatory approaches to reprogram pro-inflammatory tissue environments. Iosif is a 2022 Fellow in Antibody and Cellular Therapeutics at the Foresight Institute, and Senior Fellow at the Abigail Adams Institute. He holds degrees from Brandeis University, International Business School, and Quantic School of Business and Technology, as well as certificates from New England Complex Sciences Institute, Real World Risk Institute, and Johns Hopkins University. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/5894b2e6-042c-46b5-b989-e88ae845ee5b/ChayseNunciato.png Home - Chayse Nunciato (Undergraduate Student) Chayse Nunciato is an undergraduate honors student at the College of Charleston. She is working towards obtaining a B.S. in Biology, with the goal of attending medical school. With an ambition to take part in cellular research surrounding autoimmunity, she hopes to gain a greater understanding in the Ferreira Lab about engineered immune receptors and their impact on a cell's function. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/770175fe-8f9d-499d-9ba7-05ef61e2849d/JasonGould.jpg Home - Jason Gould (Undergraduate Student) Jason Gould is an undergraduate student at Emory University pursuing a B.S. in Neuroscience and Behavioral Biology on the pre-med track. Hoping to attend medical school, his research interests lie in immunology and regulatory T cells (Tregs), particularly their clinical applications in cancer therapy and improving outcomes in organ transplant rejection. He looks forward to deepening his understanding of CAR engineering and lentiviral transduction in the Ferreira Lab. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/249abe64-919c-48e4-89d9-b3441747fa63/JaneAnnJohnson.jpeg Home - Jane Ann Johnson (Undergraduate Student) My name is Jane Ann Johnson, and I am a rising senior at Wofford College. I am a Biology/Music Performance double major. At Wofford, I am in the concert band, secretary/treasurer of the pre-dental society, president of my sorority, and a member of United on Campus. I am from Isle of Palms, South Carolina. I love going to CorePower, playing pickleball, and traveling. My dream is to attend dental school at MUSC. This summer I hope to gain more research experience and learn about the effects of Treg cells on solid tumors. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/793bd285-fd4b-42d9-af87-a0713f756993/BurkeMounts.jpeg Home - Burke Mounts (Medical Student) Burke Mounts is a medical student at the Medical University of South Carolina (MUSC) with a background in biological sciences, economics, and medical physiology. Prior to medical school, he worked in a variety of clinical roles in orthopedic surgery, inpatient rehabilitation, and hospital medicine settings. His research interests include immune engineering, CAR T cell therapies, immune tolerance, and the development of novel cellular therapies for autoimmune disease and cancer. In the Ferreira Lab, he contributes to projects involving engineered immune receptors and regulatory T cell therapies aimed at improving the treatment of autoimmune disease and other immune-mediated conditions. Beyond immunology, Burke is interested in orthopedic disease, musculoskeletal health, and translational research that improves patient outcomes. He is also interested in systems-level improvements in healthcare delivery, including the application of technology, artificial intelligence, and process optimization to improve access, efficiency, and quality of care. Through a career that combines clinical practice, research, and innovation, Burke hopes to help bridge scientific discovery and patient care while advancing solutions to both individual patient challenges and broader healthcare system needs.. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/4412f0da-b1fb-4248-9b6e-bac33f29bb8e/hamiltonphotowebsite.png Home - Francesco Hamilton (High School Student) Francesco Hamilton is a high school student at Academic Magnet. His research interests include Oncolytic Virotherapy, Focused Ultrasound, and Volatile Organic Compound (VOC) Diagnosis. He hopes to gain a greater understanding of HLA proteins and T cell receptors (TCR) and their applications in cancer treatment. Currently pursuing a VOC-based cancer diagnosis machine, he hopes to become a researcher himself one day. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1619689252301-BKUQQKNZMNHFQAC91TM1/IMG_7585.JPG Home - This could be you! Get in touch with us. We are always looking for passionate and creative scientists at all levels to join our efforts in the study and engineering of immunology. https://www.ferreiralab.com/labmembers daily 0.75 2026-06-16 https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1618497259178-6XJGK9GR6YAVBQL5L519/20140301_Trade-151_012-2.jpg Lab members https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1632014143502-TIPDXTMPEF3XJQS27OA6/Ferreira%2CLeonardo-Microbiology.JPG Lab members - Leonardo Ferreira, PhD (Principal Investigator) Leonardo M. R. Ferreira, Ph.D. is an Assistant Professor of Microbiology and Immunology and, by courtesy, of Regenerative Medicine and Cell Biology at the Medical University of South Carolina and the Hollings Cancer Center. He holds a B.Sc. in biochemistry from University of Coimbra, Portugal, a Ph.D. in biochemistry from Harvard University, and completed a postdoctoral fellowship at the University of California, San Francisco. Fascinated by the phenomenon of immune tolerance, his long term goal is to control how the immune system defines self and non-self. Such knowledge will allow the design and development of powerful new engineered immune cell therapies to fight autoimmune disease, cancer, and aging. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/0c0c7789-b034-40cd-9b19-5cb708857b5d/AndrewBrim.jpg Lab members - Andrew Brim (PhD student) Andrew Brim is a PhD student in the Biomedical Sciences Program. He graduated from the University of Florida with his B.S. in Biochemistry. While at UF, he also worked under Dr. Steven Bruner to elucidate the structure of clinically relevant SRP54 mutant proteins by x-ray crystallography. After graduating, he joined Dr. Hong Qin’s lab at Mayo Clinic Florida, where he helped develop novel CAR-T cell therapies by performing lentivirus plasmid cloning and in vivo animal studies. He joined the Ferreira Lab in 2026 and is interested in tailoring genetic modifications to improve CAR-based cellular therapies for the solid tumor microenvironment, infectious diseases, and autoimmune diseases. Andrew enjoys reading, baking, surfing, comedy podcasts and hanging out with his beagle. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/9cd7ecfd-d69c-4ae9-adc6-0ecd43b22feb/MJValencia.jpg Lab members - MJ Valencia (PhD Student) MJ Valencia is a Ph.D. student in the Biomedical Sciences Program. She earned her bachelor’s degree in Microbiology and Immunology from The University of Texas at San Antonio. MJ is passionate about understanding the mechanisms that drive inflammation and autoimmune disease, with the goal of contributing to the development of innovative immunotherapies and targeted treatments. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/78f83434-1701-43d5-8ab4-e3436fcb7606/AvikChattopadhyay.jpg Lab members - Avik Chattopadhyay, PhD (Postdoctoral Scholar) Avik Chattopadhyay, Ph.D. is a postdoctoral scholar in the lab from India. Avik completed his B.Sc. at the University of Calcutta and M.Sc. at the Banaras Hindu University in Zoology. He earned his Ph.D. in Immunology from the Indian Institute of Science, Bangalore, under the supervision of Prof. Dipankar Nandi (who graduated with a PhD from the lab of Nobel laureate J. P. Allison). Avik’s doctoral research focused on the metabolic responses of tumor cells to interferon-gamma, a critical determinant in immunotherapy outcomes. Furthermore, his investigations led to the discovery of novel anti-inflammatory compounds identified through high-throughput screening against interferon-gamma-induced nitric oxide production. Avik has been recognized with numerous accolades, including the Sun Pharma Science Foundation Science Scholar Award 2023 in Pharmaceutical Sciences. Currently, his research as a postdoctoral scholar is dedicated to advancing precise and effective immunotherapy strategies targeting challenging cancers and inflammatory diseases. Avik aspires to establish himself as an independent researcher, fostering interdisciplinary collaborations to innovate solutions in disease biology. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/8ea07c1c-a95b-4561-99fe-c5ad24db09ae/ErinOConnor.jpg Lab members - Erin O’Connor (Research Scientist) Erin O'Connor is a recent graduate of the College of Charleston, where she obtained a B.S. in Biology with a minor in Chemistry. As a research scientist, she hopes to contribute to a greater understanding of the role of genetic engineering in treating physical and mental illnesses. In the future, she plans to pursue a Ph.D. in Genetics. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/6b961c1f-ff6b-4f5c-9f0f-4c70c5eb51b7/IosifGershteyn.jpg Lab members - Iosif Gershteyn (Visiting Scholar) Iosif M. Gershteyn is a systems immunologist focusing on harnessing computation in application to autoimmune disorders and aging. He is the Chairman of Ajax Biomedical Foundation, which supports several projects in partnership with the Ferreira lab, including the interrogation of interactions between diet and autoimmune disease and developing immunomodulatory approaches to reprogram pro-inflammatory tissue environments. Iosif is a 2022 Fellow in Antibody and Cellular Therapeutics at the Foresight Institute, and Senior Fellow at the Abigail Adams Institute. He holds degrees from Brandeis University, International Business School, and Quantic School of Business and Technology, as well as certificates from New England Complex Sciences Institute, Real World Risk Institute, and Johns Hopkins University. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/e1c2d2c7-2194-4eb3-90e7-9807a57675b9/ChayseNunciato.png Lab members - Chayse Nunciato (Undergraduate Student) Chayse Nunciato is an undergraduate honors student at the College of Charleston. She is working towards obtaining a B.S. in Biology, with the goal of attending medical school. With an ambition to take part in cellular research surrounding autoimmunity, she hopes to gain a greater understanding in the Ferreira Lab about engineered immune receptors and their impact on a cell's function. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/6f995c7f-e094-4ebe-bca1-04cc6026957c/JasonGould.jpg Lab members - Jason Gould (Undergraduate Student) Jason Gould is an undergraduate student at Emory University pursuing a B.S. in Neuroscience and Behavioral Biology on the pre-med track. Hoping to attend medical school, his research interests lie in immunology and regulatory T cells (Tregs), particularly their clinical applications in cancer therapy and improving outcomes in organ transplant rejection. He looks forward to deepening his understanding of CAR engineering and lentiviral transduction in the Ferreira Lab. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/be592767-8173-49f3-9f14-c5287dc9306e/JaneAnnJohnson.jpeg Lab members - Jane Ann Johnson (Undergraduate Student) My name is Jane Ann Johnson, and I am a rising senior at Wofford College. I am a Biology/Music Performance double major. At Wofford, I am in the concert band, secretary/treasurer of the pre-dental society, president of my sorority, and a member of United on Campus. I am from Isle of Palms, South Carolina. I love going to CorePower, playing pickleball, and traveling. My dream is to attend dental school at MUSC. This summer I hope to gain more research experience and learn about the effects of Treg cells on solid tumors. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/3efbe6ef-f1b6-437b-bd3a-09b2c18d6e7a/BurkeMounts.jpeg Lab members - Burke Mounts (Medical Student) Burke Mounts is a medical student at the Medical University of South Carolina (MUSC) with a background in biological sciences, economics, and medical physiology. Prior to medical school, he worked in a variety of clinical roles in orthopedic surgery, inpatient rehabilitation, and hospital medicine settings. His research interests include immune engineering, CAR T cell therapies, immune tolerance, and the development of novel cellular therapies for autoimmune disease and cancer. In the Ferreira Lab, he contributes to projects involving engineered immune receptors and regulatory T cell therapies aimed at improving the treatment of autoimmune disease and other immune-mediated conditions. Beyond immunology, Burke is interested in orthopedic disease, musculoskeletal health, and translational research that improves patient outcomes. He is also interested in systems-level improvements in healthcare delivery, including the application of technology, artificial intelligence, and process optimization to improve access, efficiency, and quality of care. Through a career that combines clinical practice, research, and innovation, Burke hopes to help bridge scientific discovery and patient care while advancing solutions to both individual patient challenges and broader healthcare system needs. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/785c47b9-8449-406b-a8d2-33c8afa133ef/hamiltonphotowebsite.png Lab members - Francesco Hamilton (High School Student) Francesco Hamilton is a high school student at Academic Magnet. His research interests include Oncolytic Virotherapy, Focused Ultrasound, and Volatile Organic Compound (VOC) Diagnosis. He hopes to gain a greater understanding of HLA proteins and T cell receptors (TCR) and their applications in cancer treatment. Currently pursuing a VOC-based cancer diagnosis machine, he hopes to become a researcher himself one day. https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1619735086060-HU2M9LR5DNTJ76FCYRXN/IMG_7585.JPG Lab members - This could be you! Get in touch with us. We are always looking for passionate and creative scientists at all levels to join our efforts in the study and engineering of immunology. https://www.ferreiralab.com/publications daily 0.75 2026-04-09 https://www.ferreiralab.com/protocols daily 0.75 2025-10-21 https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1629148389200-JLHVYLQTVLRE496LDX2O/Making+Media+Sterile+technique+Figure+MUSC.png Protocols https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1629148723498-VQ86ARWLO5UXZGDAG7TV/Thawing+cells+Figure+MUSC.png Protocols https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1631922879306-01LJEQYT3ZDU1SCEIX1U/Suspension+cell+culture+protocol+Figure+MUSC.png Protocols https://images.squarespace-cdn.com/content/v1/6087ba21fb7a9719cf641b98/1631922965374-BTKC9C5J2VUPVV5SWZJO/Adherent+cell+culture+protocol+Figure+MUSC.png Protocols 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